Category: weight loss tips

Overview

Stimulants are chemical substances that can temporarily accelerate activity in your body. Stimulants can range in potency and are often used in both over-the-counter and prescription supplements and medications. One common use for stimulants is for weight loss.

With the withdrawal of ephedra from the U.S. market, companies producing dietary supplements for weight loss have replaced ephedra with other stimulants to induce weight loss. Many of these stimulants contain caffeine or are very similar to caffeine.

Caffeine and related substances suppress appetite and cause increased metabolism, thus causing the body to burn more calories. The increase in metabolism causes the body to produce more heat (thermogenesis). Most of these agents are probably safe in very low doses. However, side effects increase when these products are taken in high doses or in combination with other stimulants. Especially in high doses, stimulants like caffeine have the potential to cause nervousness, insomnia, increased heart rate, high blood pressure, abnormal heartbeat, and palpitations. Caffeine also causes psychological dependence and can cause withdrawal symptoms if discontinued abruptly. The increase in metabolism caused by these agents also makes body organs, especially the heart, work harder, which can lead to side effects over the long term. Supplements that contain stimulants should be avoided by women who are pregnant or breastfeeding and by individuals with underlying heart disease or high blood pressure. Many of these supplements have not been well studied and may have other serious side effects that are unknown at this time.

Types

Stimulants can be used both in supplements and in medication. Over-the-counter stimulants, such as caffeine and synephrine, are more commonly found in weight loss supplements.

According to the National Institute on Drug Abuse, prescription stimulants are a commonly abused medication. This is due to how easy it is to develop a dependence on the drug. Prescription stimulants have the ability to increase the levels of an important neurotransmitter in the brain called dopamine. As dopamine levels rise, a pleasant feeling of euphoria occurs. As these dopamine levels are sustained at a greater level over time, the brain can develop both a dependence on and a tolerance to the stimulant. Due to addiction concerns, all prescription stimulants used for weight loss are currently controlled substances in the United States.

Many fads come and go.

There are two notable ones: one dietary, one a drug. Both of them are dangerous. The drug is ephedra, contained in the Chinese herb ma huang. Ephedra is a potent stimulant that can raise blood pressure; its use has been associated with stroke, heart attack, and death. It is found in many weight-loss products and does promote weight loss. In my opinion, however, it is not worth the risk.

Another Chinese herb, sida cordifolia, contains a different stimulant, synephrine. This substance is newer to the market and less information is available; however, I would view it with extreme caution as well. In the 1960s, the saying “speed kills” was popularized to dramatize the danger of using stimulants.

High-protein diets keep coming back to haunt nutritionists.

The latest versions are trumped up in pseudoscience suggesting that excess carbohydrates cause the body to become resistant to insulin and that this causes obesity and diabetes. The solution is to replace carbohydrates with protein. This theory is not based on scientific evidence and overlooks the fact that practically every society has always gotten most of its calories from carbohydrates.

For example, Asian diets are based on rice. If the carbohydrates-cause-obesity theory is correct, Asian cultures should be rife with obesity and diabetes, but of course they are not. The average Asian rice eater is slender. So much for the theory behind high-protein diets; These diets contradict all the advice given by good professional groups with science to back up their recommendations:’ groups including the American Academy of Pediatrics, the American Heart Association, the National Cancer Institute, the American Diabetes Association, and so on.

MISCONCEPTIONS ABOUT HERBAL AND NATURAL SUPPLEMENTS

One misconception people have about these words is that they mean a product is safe. Many herbs, vitamins, and other natural supplements are powerful substances. Any substance should be taken according to prescribed or recommended dosing directions. Taking more than the recommended dosage may result in unpleasant or serious side effects. Ephedra is one such example.

Many people also incorrectly believe that manufacturers of herbs, vitamins, and other natural supplements are required to adhere to the same strict guidelines that producers of overcounter and prescription pharmaceutical products must follow. This is not true. The lack of regulation of natural products can make it difficult to identify quality herbal ind natural remedies.
To help ease the uncertainty, the federal government passed the Dietary Supplement Health and Education Act in 1994. This act offers some consumer protection by requiring that manufacturers label their supplements with specific information about the ingredients

Ephedra, also known as ma huang –  This herbal product has been linked with more than 60 deaths and over 800 medical complaints. Many states now ban or restrict the sale of ephedra or products containing it.

Phen-Fen

If eating too much is the result of changes in the reward, learning, and habit circuits of the brain, then medicines that act on those circuits really should modify behavior and help manage this impulse of overeating. That is precisely what a mix of two drugs-phentermine and fenfluramine, typically referred to as phen-fen-seemed to do.

Phen-fen turned out to be hazardous and was pulled from the market in 1997. Occasionally, it developed serious and quite often life-threatening unwanted effects in the heart. While no one should use this pharmaceutical mixture today, we can learn a lot about the biology of overindulging by analyzing the way it worked on the brain’s reward circuits. Many physicians say phen-fen was the most efficient drug therapy they ever endured for the treatment of obesity.

Phen-fen acted in a complicated means on two brain chemicals: serotonin and dopamine.

The drug combination improved the amount of serotonin, which shuts down the act of dopamine and decreases activity in the reward pathways. The complete impact was to reduce the drive for reward.

Studies have revealed that serotonin can also tamp down the satisfying value of drugs of abuse, for example cocaine. By way of example, a test animal which has been trained to press a lever to get cocaine will minimize doing so after receiving pharmaceuticals that promote serotonin release. This might be an aid to describe reports in psychopharmacological journals that phentermine and fenfluramine reduce drug use.

If the same pharmacologic therapy reduces the power that both food and drugs of abuse can gain over the body, then they are in all probability engaging the same regions of the brain. Which means the reward circuits targeted by highly palatable food are also the reward circuits targeted by drugs.

Rewarding foods tend to be reinforcing, meaning that they keep us coming back for more. I put an M&M in my mouth, it tastes good, and I return for another. The sugar and fat in the candy reinforce my desire to keep eating it.

Scientists ask two questions to determine whether animals find a substance reinforcing:

Are they willing to work to obtain it?

Do they respond to other stimuli they’ve learned to associate with the substance?

By these criteria, sugar, fat, and salt are clearly reinforcing. One decisive piece of evidence is exquisitely simple. French researchers first allowed one group of animals to eat freely while restricting the diet of another group. Next they measured the speed at which each group ran for chow compared to Choc and Crisp, a German chocolate-flavored cereal high in sugar and fat.

There have been many studies on animals especially mice that confirms the fact that sugar, fat, and salt are clearly reinforcing and the animals are willing to work hard to get these foods.

My own look at a vanilla milkshake confirmed the reinforcing value of sugar and fat and helped me better understand what matters most.

The power of the vanilla milkshake and other high-sugar, highfat foods is further amplified as cues become associated with them.

When we put food rich in sugar, fat, and salt in our mouths, we stimulate neurons, which are the basic cells of the brain. Neurons are connected in circuits and communicate with one another to create feelings, store information, and control behavior. They respond to rewarding foods by firing electrical signals and releasing brain chemicals that then travel to interconnected neurons. We say those neurons are “encoded” for palatability.

The neurons in the brain that are stimulated by taste and other properties of highly palatable food are part of the opioid circuitry, which is the body’s primary pleasure system. The “opioids,” also known as endorphins, are chemicals produced in the brain that have rewarding effects similar to drugs such as morphine and heroin.

Stimulating the opioid circuitry with food drives us to eat.

A significant number of patients try to take low-calorie diet, weight-loss drugs and stimulant based fat burners, but they experience weight loss only for a short period of time. After a year or two, they return to their original size and shape without even knowing it. That is because it is not weight loss itself which is difficult; it is maintenance. And maintenance can only be achieved by behavior therapy.

If one is to start to change something, it is not diet or exercise plan; it is behavior. Behavior dictates one’s lifestyle, which in turn affects one’s health. For example, high stress can lead to overeating. People who are in a period of emotional turmoil (such as the loss of a loved one) often eat to cope with their problems. Thus, beyond dieting and physical activity, stress-reducing techniques and learning how to cope with emotional problems (with the help of a support group or counselor) are necessary steps to losing weight. All of these behavioral changes can lead to an improved weight management.

The doctor plays a major role in achieving the patient’s weight loss. The said professional has to assess the patient’s motivation for losing weight. And aside from that, he or she has to suggest ways on how to actually lose those extra pounds. The doctor’s motivation and encouragement are the key components to the program.

Moreover, the doctor has to understand the patient’s weight problem (when and how he or she puts on weight). He or she must be aware that most of the patients he or she is handling are victims of shame and hurtful comments from others. He or she must also be knowledgeable of the possible health risks that go along with being obese. Realizing these things can help the doctor motivate and encourage the patients to achieve his or her weight goals. The patient, in his or her part, must realize, however, that losing weight is a commitment that he or she must work at to be successful.

Sometimes the person on a weight loss program finds that he or she is not losing weight. There are several questions that can be asked to a person in this situation to understand what may be happening. Has the person been under stress? Did he or she sustain an injury that interferes with or prevents exercise? Has the person become bored with his or her routine? Answering questions like these can help a person make adjustments that will help him or her achieve his or her goals. Sometimes, a person limiting his or her caloric intake feels deprived and eats more, especially fat-filled foods. Making dietary changes that are small and easier to adopt (for example, eating with a smaller plate than usual) may be a possible solution.

Behavior therapy with low-fat diet, reduced caloric intake, and increased physical activity comprise an effective weight loss program. All of these combined is what makes the patient more likely to maintain his or her weight loss. Changing one’s behavior, certainly, is the first step that must be taken to achieve the final goal. Weight loss drugs and surgery must be pursued only when necessary. This helps eliminate unwanted side effects or harm on the body. As a conclusion, willpower, learning how to lose weight safely, and understanding that the weight loss process has its ups and downs are all needed for successful weight loss and management.

1. Learning how to read nutrition labels. This can help a person determine how many calories a particular food item has and also understand how much fat, carbohydrate, and protein is contained in a food.

2. Learning new strategies for purchasing foods (for example, buying low-calorie foods).

3. Learning methods for food preparation that incorporate lower amounts of oil and fat (for example, using margarine instead of butter or oil to prepare fried chicken, or baking instead of frying).

4. Drinking more water. People— even those who are not trying to lose weight—should be in the habit of drinking 6 to 8 8-ounce glasses of water every day.

5. Learning how to choose correct portion sizes.

6. Learning to substitute low-calorie snacks to help curb the appetite (for example, eating celery and carrot sticks instead of filling up on potato chips).

7. Avoiding alcohol consumption, because alcohol (beer, wine, and other hard liquors) is high in calories.

DRUGS APPROVED BY THE FDA FOR WEIGHT LOSS

Drugs approved for use in weight loss programs can be broken down into the following categories:

1. Anorexiants (drugs that work on chemicals in the brain)

b. Sibutramine (Meridia®)

Drugs that work in the brain are considered appetite suppressants. Amphetamines are approved for use in treating other diseases; their use as a weight loss drug is considered “off label,” or not approved. Doctors often prescribe drugs for “off-label” use, meaning that the drug is used at a different dose, for a longer time, or for a different medical condition than was approved by the FDA. Off-label prescribing is a common, and legal, practice.

Amphetamines, which have appetite-suppressing effects, are approved by the FDA for weight loss, but only for short term use (12 weeks or less). Only a handful of studies have evaluated their use for periods longer than six months. Scientists do not fully understand how amphetamines and amphetamine- like drugs work. It is believed that these drugs cause the release of norepinephrine and dopamine, two chemical messengers that control hunger, in the brain. In addition, it is thought that amphetamines decrease the sharpness of a person’s senses of smell and taste, which ultimately results in appetite-suppressing properties. Another benefit of amphetamines is that they allow someone who is obese or overweight the opportunity and time to learn proper weight loss techniques, such as diet and exercise. Because they are addictive, amphetamines are not often recommended for use in weight loss. Amphetamines and amphetamine-like drugs only bring about a very small amount of weight loss (3–8% decrease in weight when compared to placebo). So, since amphetamines are addictive and not very effective for long-term weight control, they are not recommended for weight loss. Amphetamines and amphetamine-like drugs only bring about a very small amount of weight loss. The usual weight loss that occurs is only 5 to 10 pounds. Often, the weight loss effects only last for a few weeks.The way these drugs help induce weight loss is by providing the patient the time and opportunity he or she needs to learn proper weight loss techniques.

2. Lipase Inhibitors (drugs that prevent fat from being absorbed into the bloodstream)

a. Orlistat®

Fat absorption inhibitors work by suppressing gastric and pancreatic lipases, the enzymes that breakdown triglycerides in the intestine. When lipase action is blocked, triglycerides from the diet will not be hydrolyzed into absorbable free fatty acids, and are passed out of the body undigested instead.

The Obesity Epidemic

Hello. My name is Ana, I’m 17 years old, and I weigh 340 pounds (155 kg). I’ve been overweight since I was 12 years old. I used to go to school, but I dropped out because people make fun of me. I have missed my entire time in high school because of being obese. I suffer from depression, anxiety, and a fear of leaving my house. I hate my body so much it’s insane. I wish I could lose all this weight in a heartbeat, but I know it is not possible. All I am able to do is sit around in the house all day. When I do go out, I can’t bring myself to get out of the car. I joined a gym, but I don’t know what good that’s going to do; I am too embarrassed even to go. I feel so guilty for letting myself get so big. I wish I could just live an ordinary teenage life and have cute boys look at me and not pick on me. I wish I could go out and enjoy life instead of being afraid all the time. I wish I could simply go to a store and buy sexy clothing, bell-bottoms, tank tops, and a bikini, but I can’t because they don’t make that kind of clothing in my size. I know I’m not the only obese person in the world, but being a teenager and watching all these other skinny teenage girls makes me feel like I am the only [obese] one. I feel like such a freak. I wish I could change, but it’s so hard. I really need some support right now. I wish all these pretty, skinny, in-shape people could just respect me, but that will never happen because of the way I look.

This is one of the many stories that describe how an adolescent feels when he or she is obese. Overweight and obesity are growing problems. These conditions have reached epidemic proportions in the United States and in most industrialized nations around the world. An explosion in the variety and availability of high-calorie, high-fat convenience foods and the fact that people are exercising less and performing less manual labor have added to the problem.

HEALTH RISKS ASSOCIATED WITH OBESITY

Obesity is currently the second leading cause of preventable death in the United States. Being overweight and obese can contribute to death by causing or worsening many different diseases, including but not limited to:
• High blood pressure;
• High cholesterol (overweight individuals often have higher levels of “bad” cholesterol and lower levels of “good” cholesterol);
• Obstructive sleep apnea (a condition where a person may stop breathing for a period of time while sleeping);
• Rheumatoid arthritis and osteoarthritis;
• Certain types of cancer, including breast, esophageal, stomach, colorectal, endometrial, and kidney cancer;
• In women: menstrual disturbances, infertility problems, and an increased incidence of birth defects in children;
• Increased daytime sleepiness and heat intolerance;
• Obesity may also contribute to gallbladder disease, gout, breathing problems, increased incidence of infections, liver diseases, and increased pain, especially in the lower back and knees.

A person’s risk of developing these health conditions increases as his or her BMI increases, so obese individuals are at higher risk than overweight individuals. Weight loss of even 10 to 15 pounds (4.5 to 6.8 kg) in adults and children can decrease the risk of developing health problems such as diabetes and hypertension. This weight loss can also help to control or lessen the severity of these conditions in patients already afflicted with these conditions. As previously noted, adults with central obesity are at higher risk of developing many of these conditions than are people with evenly distributed body fat.

In the United States, approximately 30% of children and adolescents ages 6 to 19 are overweight and 15% are obese. Children and adolescents who are overweight are more likely to be overweight as adults. Overweight children ages 10 to 14 who have at least one overweight or obese parent were reported to have an almost 80% chance of remaining overweight as they enter adulthood.

WHEN ARE DIET PILLS RECOMMENDED?

The question of when and how diet pills should be used should be answered. Overall, in carefully selected patients, a doctor may prescribe appropriate drugs to be used in conjunction with diet and exercise to achieve weight loss. The only drugs recommended for use by the National Heart, Lung, and Blood Institute (NHLBI) are those that have been approved by the U.S. Food and Drug Administration (FDA). FDA-approved drugs have been studied and determined to be safe and effective for some, but not all, people. 

According to the NHLBI, people who are appropriate candidates and should consider taking diet pills are adults with a BMI of greater than 30 kg/m2 or those with a BMI of higher than 27 kg/m2 who have health problems related to being overweight. Diet pills, like any other medication, have risks associated with their use. Therefore, diet pills should only be used by people who are at high risk of developing weight-related health problems. For people who are obese or overweight, the benefits of weight loss are generally greater than the risks associated with taking diet pills. Several diet pills have been studied for use in children; however, doctors only recommend using them in extreme situations.
 

The National Institutes of Health (NIH) has established guidelines on the use of diet pills. These guidelines are used by health-care practitioners both within and outside the United States. The information contained in these guidelines helps to determine who should and should not use weight loss medications. This is important because people who use diet pills inappropriately risk potentially devastating effects on their health.

The government is warning you to stay away from nearly 30 weight-loss products that contain unlisted and possibly dangerous ingredients. The pills are advertised as “natural” fat busters and have intriguing names like Imelda Perfect Slim and Zhen de Shou. Some suggest they are innovative “herbal” remedies from Asia. But the Food and Drug Administration on Monday said the concoctions contain unlisted ingredients, including powerful appetite-suppressing drugs and a suspected carcinogen.

“These tainted weight loss products pose a great risk to public health because they contain undeclared ingredients and in some cases prescription drugs in amounts that greatly exceed their maximum recommended dosages,” said Dr. Janet Woodcock, who directs the FDA’s drug evaluation center.

FDA lab testing found 28 dietary supplements that could land unsuspecting users in the emergency room. Many contain sibutramine, a powerful Appetite suppressant that’s a chemical cousin of amphetamines. It can cause heart attacks, strokes, heart palpitations and other problems. Some contain phenolphthalein, a chemical long used as a laxative, but which is now being withdrawn from the market because of cancer risks.

The FDA is considering criminal charges against some of the companies, because they have not responded to requests for recalls.
The products are:
Fatloss Slimming, 2 Day Diet, 3x Slimming Power, 5x Imelda Perfect Slimming, 3 Day Diet Japan Lingzhi, 24 Hours Diet, 7 Diet Day/Night Formula, 7 Day Herbal Slim, 8 Factor Diet, 999 Fitness Essence, Extrim Plus and GMP.
Also:
Imelda Perfect Slim, Lida DaiDaihua, Miaozi Slim Capsules, Perfect Slim, Perfect Slim 5x, Phyto Shape, ProSlim Plus, Royal Slimming Formula, Slim 3 in 1, Slim Express 360, Slimtech, Somotrin, Superslim, TripleSlim, Zhen de Shou, Venom Hyperdrive 3.0

Before choosing a weight loss diet pill, it is very important to understand how they work, what are the different kinds of weight loss pills and what will be the best options for you.