WEIGHT LOSS PILL TYPE: An Appetite suppressant that is chemically related to amphetamines. It is a schedule III controlled substance, with moderate potential for abuse.
SOLD AS: Benzphetamine is available in 25-mg and 50-mg immediate-release tablets and 75-mg controlled-release tablets. Also contains inactive ingredients: calcium stearate, cornstarch; ervthrosine sodium; FD 8 C yellow No. 61; lactose; providone; sorbitol.
RESEARCH: Benzphetamine was approved for weight management by the Food and Drug Administration in 1960; therefore most of the research studies are quite dated. One of the early studies was published in Drugs, in which benzphetarnine was identified as an addictive substance. Other studies, many of which were conducted in Europe, substantiated its usefulness as a weight-loss aid when combined with a low-calorie diet and exercise. These and others studies are listed in Further Information.
WHAT IS IT SUPPOSED TO DO: Benzphetamine stimulates the satiety (feeling of fullness) center in the hypothalamus and limbic regions of the brain, where appetite and hunger are controlled. When benzphetamine is used along with a lowcalorie diet, behavior modification, and a regular exercise program, it can increase the amount of weight lost by about 10 percent. However, weight loss may be temporary only, especially after the drug is discontinued. To maintain weight loss or to continue to lose additional weight after stopping benzphetarnine, it is necessary to follow a sensible eating plan and an exercise program.
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[tab title=”HOW TO TAKE IT:“] Treatment should be individualized and determined by your physician, based on your needs. Benzphetamine can be taken as a single 75-mg (sustained release) dose in midmorning or midafternoon, or the regular tablets (25- or 50-mg) can be taken .on an empty stomach 1 hour before meals. Maximum dosage is 150 mg per day.
Do not take a double dose. If you miss a dose and it is almost time for your next one or it is late afternoon or later, skip the missed dose and wait until your next scheduled dose.[/tab]
[tab title=”SIDE EFFECTS:“]The most common side effects include nervousness; irritability; headache; sweating; dry mouth; nausea; insomnia and constipation. Some individuals experience palpitations and an increase in blood pressure. .
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[tab title=”PRECAUTIONS:“]Do not take benzphetamine if you are also taking an MAO inhibitor or any central nervous system stimulants; or if you have any of the following conditions: arteriosclerosis, or hardening of the arteries; cardiovascular disease; hypertension; glaucoma; or hyperthyroidism. Do not use this drug if you are or may become pregnant, as it can harm the fetus. Abuse of benzphetamine can cause psychological dependence and severe social dysfunction.
Benzphetamine, like other appetite suppressants, often causes dry mouth, which can increase the chance of developing gum disease and dental cavities. Special attention to oral hygiene, including use of sugarless gum and sugarless hard candies, or sucking on ice chips, is recommended while taking this drug.
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